Diet metabolic research
Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Weight management through lifestyle modification for the prevention and management of type 2 diabetes: rationale and strategies: a statement of the American Diabetes Association, the North American Association for the Study of Obesity, and the American Society for Clinical Nutrition. Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. Assessments during inpatient hospital admissions and under free-living conditions occurred during the weight monitoring period and at the end of each test diet period. A primary end-point event occurred in 288 participants. Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM. Long-term weight loss maintenance in the United States. Meal-induced thermogenesis and macronutrient oxidation in lean and obese women after consumption of carbohydrate-rich and fat-rich meals. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Baseline Characteristics of the Study Participants a View Large Download Table 3. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. Full Text of Methods. Details of the trial design are provided elsewhere.
org. Composition of the Run-in and Test Diets During Weight-Loss Maintenance (per 2000 kcal) View Large Download Table 2. Glycemic index of foods: a physiological basis for carbohydrate exchange. None of the sponsors had any role in the trial design, data analysis, or reporting of the results. Long-term persistence of hormonal adaptations to weight loss. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial. On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. Supplemental Content Ebbeling CB, Swain JF, Feldman HA, et al. Connected lines indicate individual outcomes for each participant. All participants provided written informed consent. The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). Study Design of the Run-in and Test Phases View Large Download Body composition was assessed during the weight monitoring period of the run-in phase and following weight loss. 8 years. Beginning on October 1, 2003, participants were randomly assigned, in a 1:1:1 ratio, to one of three dietary intervention groups: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with nuts, or a control diet. Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. Immediately before the 3-day inpatient hospital admission, the assessments under free-living conditions were conducted over 14 (total energy expenditure) or 7 (physical activity) days.
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Diet metabolic research
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